Tag Archives: Early Menopause

Early Menopause and lack of child birth increase risks for Heart Failure

Heart Health in Women has many risk factors associated with it. A new study, another retrospective one, examined 28,516 women, who were enrolled as part of the Women’s Health Initiative (link below), a great effort that is now providing invaluable statistics that can be used to identify root causes and create awareness.

Eliminating all other known factors, such as BMI, smoking etc., two new factors popped up:

  1. Early Menopause
  2. Lack of pregnancy

They also identified that for every year’s worth of delay in menopause initiation, a woman’s heart failure rate drops by 1%. The other risk is caused by nulliparity, or lack of pregnancy. I am quoting directly here:

The latest study also found that women who had never given birth were 2.75 times more likely to have diastolic heart failure than women who had children.

The study authors did not establish a direct causal link, but they were able to identify a statistical link. The lead author did mention that polycystic ovary syndrome (a blog post for another day) has been known to increase cardiovascular risk. Diastolic Heart Failure happens when the heart is not able to pump enough blood to the body.

Study Limitations

Retrospective studies, especially ones based on efforts such as the Women’s Health Initiative, where large amount of data can be a treasure trove of information, just as this study has been. However, there are limitations. The current study only shows an association, not a causation, and no clues on the actual causation.

Such limitations however can be overcome by future studies, that focus on trying to identify causes.

Mitigating Circumstances

The more causes that are identified for the risk of heart failure, the better. Instead of considering these things in a negative light, women and doctors can better prepare ahead, taking precautionary measures ensuring a long and fruitful lifespan. It is also true that women in this century, prefer to make their life choices and therefore, knowing that avoiding pregnancy means a need to plan and prepare ahead for optimal health is always very good!

References:

  1. The study (sits behind a paywall): http://www.sciencedirect.com/science/article/pii/S0735109717367694
  2. The Guardian Article summarizing the study: https://www.theguardian.com/science/2017/may/15/earlier-menopause-puts-women-at-greater-risk-of-heart-failure-study-shows
  3. The Women’s Health Initiative: https://www.nhlbi.nih.gov/whi/
  4. Nulliparity: http://medical-dictionary.thefreedictionary.com/nulliparity
  5. A simple review of early menopausehttp://www.webmd.com/menopause/guide/premature-menopause-symptoms#1
  6. Diastolic Heart Failure: http://www.webmd.com/heart-disease/heart-failure/tc/diastolic-heart-failure-topic-overview#1
  7. Image Courtesy, Pexelshttps://www.pexels.com/photo/sunset-hands-love-woman-5390/

Some secrets of the relationship between Vitamin D and Calcium Intake to Early Menopause revealed

A Cholla Dusk

Early Menopause

Early Menopause is generally detrimental to a woman’s health and mental well being. Thus it is important that factors that delay early menopause are exposed and women are prescribed appropriate remedies.

Limitations in the reported study

This particular study (link below) tried to differentiate Vitamin D and Calcium intake through food and through supplements. The article that talks about this study reveals some key limitations of the study, with respect to the number of people who take large quantities of supplements, enrolled as well as the fact that the subjects are predominantly Caucasian. Because the diet data was self-reported, that offers a problem as well. It is a little saddening to see an NIH funded study take on such a form.

They did account for factors such as smoking, alcohol, BMI etc.

For many of the explanations though, there are only theories and hypotheses offered. This, I am sure, is because it will take thorough, large scale studies before they can be proven.

Interesting Results

Despite the fact that at least the article tries to conclude that food-based intake of Calcium and Vitamin D is the primary driver of the push-back on early menopause, as opposed to supplemental intake, I am not sure the study lays this out for us to subscribe to, with enough confidence.

In general, it appears that taking in recommended levels of Calcium and Vitamin D, either through food, supplements, or in the case of Vitamin D, safe exposure to sun (a problem for Caucasians with their high risk to skin cancer, and perhaps a factor in the recruitment for the study, which if true, is perhaps explained better in the paper, which unfortunately sits behind a paid wall), reduces the risk of early menopause.

Conclusion

As stated, early menopause comes with significant health and financial burden to the women and health systems in the general. Therefore, not only should the results of such studies be used, they should be expanded to solidify evidence, and diversify it based on race and other factors.

Reference:

  1. A summary of the study: http://www.medpagetoday.com/endocrinology/menopause/65189